In Vitro Activities of Piperaquine, Lumefantrine, and Dihydroartemisinin in Kenyan Plasmodium falciparum Isolates and Polymorphisms in pfcrt and pfmdr1

We have analyzed the in vitro chemosensitivity profiles of 115 Kenyan isolates for chloroquine (CQ), piperaquine, lumefantrine (LM), and dihydroartemisinin in association with polymorphisms in pfcrt at codon 76 and pfmdr1 at codon 86, as well as with variations of the copy number of pfmdr1. The medi...

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Библиографические подробности
Главные авторы: Mwai, Leah, Kiara, Steven M., Abdirahman, Abdi, Pole, Lewa, Rippert, Anja, Diriye, Abdi, Bull, Pete, Marsh, Kevin, Borrmann, Steffen, Nzila, Alexis
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2009
Предметы:
Susceptibility
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786317/
https://ncbi.nlm.nih.gov/pubmed/19770282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00638-09
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