In Vitro Activities of Piperaquine, Lumefantrine, and Dihydroartemisinin in Kenyan Plasmodium falciparum Isolates and Polymorphisms in pfcrt and pfmdr1

We have analyzed the in vitro chemosensitivity profiles of 115 Kenyan isolates for chloroquine (CQ), piperaquine, lumefantrine (LM), and dihydroartemisinin in association with polymorphisms in pfcrt at codon 76 and pfmdr1 at codon 86, as well as with variations of the copy number of pfmdr1. The medi...

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Bibliografski detalji
Glavni autori: Mwai, Leah, Kiara, Steven M., Abdirahman, Abdi, Pole, Lewa, Rippert, Anja, Diriye, Abdi, Bull, Pete, Marsh, Kevin, Borrmann, Steffen, Nzila, Alexis
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Susceptibility
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786317/
https://ncbi.nlm.nih.gov/pubmed/19770282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00638-09
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