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Kinetic Analysis of Amyloid Formation in the Presence of Heparan Sulfate: FASTER UNFOLDING AND CHANGE OF PATHWAY

A number of human diseases are associated with the conversion of proteins from their native state into well defined fibrillar aggregates, depositing in the extracellular space and generally termed amyloid fibrils. Heparan sulfate (HS), a glycosaminoglycan normally present in the extracellular matrix...

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Autori principali: Motamedi-Shad, Neda, Monsellier, Elodie, Torrassa, Silvia, Relini, Annalisa, Chiti, Fabrizio
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785621/
https://ncbi.nlm.nih.gov/pubmed/19700762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.018747
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