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The Ternary Structure of the Double-headed Arrowhead Protease Inhibitor API-A Complexed with Two Trypsins Reveals a Novel Reactive Site Conformation

The double-headed arrowhead protease inhibitors API-A and -B from the tubers of Sagittaria sagittifolia (Linn) feature two distinct reactive sites, unlike other members of their family. Although the two inhibitors have been extensively characterized, the identities of the two P1 residues in both API...

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Autors principals: Bao, Rui, Zhou, Cong-Zhao, Jiang, Chunhui, Lin, Sheng-Xiang, Chi, Cheng-Wu, Chen, Yuxing
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785355/
https://ncbi.nlm.nih.gov/pubmed/19640842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.022095
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