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The Ternary Structure of the Double-headed Arrowhead Protease Inhibitor API-A Complexed with Two Trypsins Reveals a Novel Reactive Site Conformation

The double-headed arrowhead protease inhibitors API-A and -B from the tubers of Sagittaria sagittifolia (Linn) feature two distinct reactive sites, unlike other members of their family. Although the two inhibitors have been extensively characterized, the identities of the two P1 residues in both API...

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Autori principali: Bao, Rui, Zhou, Cong-Zhao, Jiang, Chunhui, Lin, Sheng-Xiang, Chi, Cheng-Wu, Chen, Yuxing
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785355/
https://ncbi.nlm.nih.gov/pubmed/19640842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.022095
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