CTG/CAG Repeat Instability Is Modulated by the Levels of Human DNA Ligase I and Its Interaction with Proliferating Cell Nuclear Antigen: A DISTINCTION BETWEEN REPLICATION AND SLIPPED-DNA REPAIR

Mechanisms contributing to disease-associated trinucleotide repeat instability are poorly understood. DNA ligation is an essential step common to replication and repair, both potential sources of repeat instability. Using derivatives of DNA ligase I (hLigI)-deficient human cells (46BR.1G1), we asses...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: López Castel, Arturo, Tomkinson, Alan E., Pearson, Christopher E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2009
Aiheet:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785351/
https://ncbi.nlm.nih.gov/pubmed/19628465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.034405
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia