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Overexpression of the chromosomally encoded aminoglycoside acetyltransferase eis confers kanamycin resistance in Mycobacterium tuberculosis

The emergence of multidrug-resistant (MDR) tuberculosis (TB) highlights the urgent need to understand the mechanisms of resistance to the drugs used to treat this disease. The aminoglycosides kanamycin and amikacin are important bactericidal drugs used to treat MDR TB, and resistance to one or both...

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書誌詳細
主要な著者: Zaunbrecher, M. Analise, Sikes, R. David, Metchock, Beverly, Shinnick, Thomas M., Posey, James E.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785282/
https://ncbi.nlm.nih.gov/pubmed/19906990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907925106
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