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Overexpression of the chromosomally encoded aminoglycoside acetyltransferase eis confers kanamycin resistance in Mycobacterium tuberculosis

The emergence of multidrug-resistant (MDR) tuberculosis (TB) highlights the urgent need to understand the mechanisms of resistance to the drugs used to treat this disease. The aminoglycosides kanamycin and amikacin are important bactericidal drugs used to treat MDR TB, and resistance to one or both...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Zaunbrecher, M. Analise, Sikes, R. David, Metchock, Beverly, Shinnick, Thomas M., Posey, James E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785282/
https://ncbi.nlm.nih.gov/pubmed/19906990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907925106
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