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Structure-based Mechanism of ADP-ribosylation by Sirtuins
Sirtuins comprise a family of enzymes found in all organisms, where they play a role in diverse processes including transcriptional silencing, aging, regulation of transcription, and metabolism. The predominant reaction catalyzed by these enzymes is NAD(+)-dependent lysine deacetylation, although so...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785207/ https://ncbi.nlm.nih.gov/pubmed/19801667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.024521 |
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