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Role of the Rad52 Amino-terminal DNA Binding Activity in DNA Strand Capture in Homologous Recombination
Saccharomyces cerevisiae Rad52 protein promotes homologous recombination by nucleating the Rad51 recombinase onto replication protein A-coated single-stranded DNA strands and also by directly annealing such strands. We show that the purified rad52-R70A mutant protein, with a compromised amino-termin...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785170/ https://ncbi.nlm.nih.gov/pubmed/19812039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.057752 |
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