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Generation of Long RNA Chains in Water

The synthesis of RNA chains from 3′,5′-cAMP and 3′,5′-cGMP was observed. The RNA chains formed in water, at moderate temperatures (40–90 °C), in the absence of enzymes or inorganic catalysts. As determined by RNase analyses, the bonds formed were canonical 3′,5′-phosphodiester bonds. The polymerizat...

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Detalhes bibliográficos
Main Authors: Costanzo, Giovanna, Pino, Samanta, Ciciriello, Fabiana, Di Mauro, Ernesto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785163/
https://ncbi.nlm.nih.gov/pubmed/19801553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.041905
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