Triple N-Glycosylation in the Long S5-P Loop Regulates the Activation and Trafficking of the Kv12.2 Potassium Channel

Mammalian voltage-dependent potassium (Kv) channels regulate the excitability of nerve and muscle cells. Kv12.2 features the longest S5-P loop among all known mammalian Kv channels with the most N-linked glycosylation sites (three sites). Despite its unique structural features, Kv12.2 is not well ch...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Noma, Kentaro, Kimura, Kazushi, Minatohara, Keiichiro, Nakashima, Hisako, Nagao, Yasuaki, Mizoguchi, Akira, Fujiyoshi, Yoshinori
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2009
Θέματα:
Membrane Transport, Structure, Function, and Biogenesis
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785156/
https://ncbi.nlm.nih.gov/pubmed/19808681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.021519
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