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A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease

More than 80 years after iron accumulation was initially described in the substantia nigra (SN) of Parkinson's disease (PD) patients, the mechanisms responsible for this phenomenon are still unknown. Similarly, how iron is delivered to its major recipients in the cell – mitochondria and the res...

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Main Authors: Mastroberardino, Pier Giorgio, Hoffman, Eric K., Horowitz, Maxx P., Betarbet, Ranjita, Taylor, Georgia, Cheng, Dongmei, Na, Hye Mee, Gutekunst, Claire-Anne, Gearing, Marla, Trojanowski, John Q., Anderson, Marjorie, Chu, Charleen T., Peng, Junmin, Greenamyre, J. Timothy
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784936/
https://ncbi.nlm.nih.gov/pubmed/19250966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2009.02.009
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