Modeling Pathogenesis and Treatment of Familial Dysautonomia using Patient Specific iPSCs

The isolation of human induced pluripotent stem cells (iPSCs)1-3 offers a novel strategy for modeling human disease. Recent studies have reported the derivation and differentiation of disease-specific human iPSCs4-7. However, a key challenge in the field is the demonstration of disease-related pheno...

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Detalhes bibliográficos
Principais autores: Lee, Gabsang, Papapetrou, Eirini P., Kim, Hyesoo, Chambers, Stuart M., Tomishima, Mark J., Fasano, Christopher A., Ganat, Yosif M., Menon, Jayanthi, Shimizu, Fumiko, Viale, Agnes, Tabar, Viviane, Sadelain, Michel, Studer, Lorenz
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784695/
https://ncbi.nlm.nih.gov/pubmed/19693009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08320
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