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Chemical Gradient-mediated Melting Curve Analysis for Genotyping of Single Nucleotide Polymorphisms
This report describes a microfluidic solid-phase Chemical Gradient-mediated Melting Curve Analysis (CGMCA) method for single nucleotide polymorphism (SNP) analysis. The method is based on allele-specific denaturation to discriminate mismatched (MM) from perfectly matched (PM) DNA duplexes upon expos...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2784656/ https://ncbi.nlm.nih.gov/pubmed/19593749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elps.200800729 |
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