Outer mitochondrial membrane localization of apoptosis-inducing factor: mechanistic implications for release

Poly(ADP-ribose) polymerase-1-dependent cell death (known as parthanatos) plays a pivotal role in many clinically important events including ischaemia/reperfusion injury and glutamate excitotoxicity. A recent study by us has shown that uncleaved AIF (apoptosis-inducing factor), but not calpain-hydro...

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Detalhes bibliográficos
Main Authors: Yu, Seong-Woon, Wang, Yingfei, Frydenlund, Didrik S, Ottersen, Ole Petter, Dawson, Valina L, Dawson, Ted M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Neurochemistry 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784601/
https://ncbi.nlm.nih.gov/pubmed/19863494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/AN20090046
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