Enrichment of sequencing targets from the human genome by solution hybridization

To exploit fully the potential of current sequencing technologies for population-based studies, one must enrich for loci from the human genome. Here we evaluate the hybridization-based approach by using oligonucleotide capture probes in solution to enrich for approximately 3.9 Mb of sequence target....

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Detalhes bibliográficos
Main Authors: Tewhey, Ryan, Nakano, Masakazu, Wang, Xiaoyun, Pabón-Peña, Carlos, Novak, Barbara, Giuffre, Angelica, Lin, Eric, Happe, Scott, Roberts, Doug N, LeProust, Emily M, Topol, Eric J, Harismendy, Olivier, Frazer, Kelly A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784331/
https://ncbi.nlm.nih.gov/pubmed/19835619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2009-10-10-r116
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