Pre-capture multiplexing improves efficiency and cost-effectiveness of targeted genomic enrichment

BACKGROUND: Targeted genomic enrichment (TGE) is a widely used method for isolating and enriching specific genomic regions prior to massively parallel sequencing. To make effective use of sequencer output, barcoding and sample pooling (multiplexing) after TGE and prior to sequencing (post-capture mu...

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Detalhes bibliográficos
Main Authors: Shearer, A Eliot, Hildebrand, Michael S, Ravi, Harini, Joshi, Swati, Guiffre, Angelica C, Novak, Barbara, Happe, Scott, LeProust, Emily M, Smith, Richard JH
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534602/
https://ncbi.nlm.nih.gov/pubmed/23148716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-618
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