Pre-capture multiplexing improves efficiency and cost-effectiveness of targeted genomic enrichment

BACKGROUND: Targeted genomic enrichment (TGE) is a widely used method for isolating and enriching specific genomic regions prior to massively parallel sequencing. To make effective use of sequencer output, barcoding and sample pooling (multiplexing) after TGE and prior to sequencing (post-capture mu...

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Bibliografiske detaljer
Main Authors:	Shearer, A Eliot, Hildebrand, Michael S, Ravi, Harini, Joshi, Swati, Guiffre, Angelica C, Novak, Barbara, Happe, Scott, LeProust, Emily M, Smith, Richard JH
Format:	Artigo
Sprog:	Inglês
Udgivet:	BioMed Central 2012
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3534602/ https://ncbi.nlm.nih.gov/pubmed/23148716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-618
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Pre-capture multiplexing improves efficiency and cost-effectiveness of targeted genomic enrichment

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