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Synthetic lethality: a framework for the development of wiser cancer therapeutics

The challenge in medical oncology has always been to identify compounds that will kill, or at least tame, cancer cells while leaving normal cells unscathed. Most chemotherapeutic agents in use today were selected primarily for their ability to kill rapidly dividing cancer cells grown in cell culture...

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Autor principal: Kaelin, William G
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784312/
https://ncbi.nlm.nih.gov/pubmed/19863774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm99
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