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Development of Synthetic Lethality Anticancer Therapeutics: Miniperspective
[Image: see text] The concept of synthetic lethality (the creation of a lethal phenotype from the combined effects of mutations in two or more genes) has recently been exploited in various efforts to develop new genotype-selective anticancer therapeutics. These efforts include screening for novel an...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4205018/ https://ncbi.nlm.nih.gov/pubmed/24893124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm500415t |
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