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Development of Synthetic Lethality Anticancer Therapeutics: Miniperspective

[Image: see text] The concept of synthetic lethality (the creation of a lethal phenotype from the combined effects of mutations in two or more genes) has recently been exploited in various efforts to develop new genotype-selective anticancer therapeutics. These efforts include screening for novel an...

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Autor principal: Fang, Bingliang
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205018/
https://ncbi.nlm.nih.gov/pubmed/24893124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm500415t
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