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Synthetic lethality in lung cancer and translation to clinical therapies

Lung cancer is a heterogeneous disease consisting of multiple histological subtypes each driven by unique genetic alterations. Despite the development of targeted therapies that inhibit the oncogenic mutations driving a subset of lung cancer cases, there is a paucity of effective treatments for the...

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Bibliografische gegevens
Gepubliceerd in:Mol Cancer
Hoofdauteurs: Leung, Ada W. Y., de Silva, Tanya, Bally, Marcel B., Lockwood, William W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041331/
https://ncbi.nlm.nih.gov/pubmed/27686855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-016-0546-y
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