A Genetically Engineered Adenovirus Vector Targeted to CD40 Mediates Transduction of Canine Dendritic Cells and Promotes Antigen-Specific Immune Responses In Vivo

Targeting viral vectors encoding tumor-associated antigens to dendritic cells (DCs) in vivo is likely to enhance the effectiveness of immunotherapeutic cancer vaccines. We have previously shown that genetic modification of adenovirus (Ad) 5 to incorporate CD40 ligand (CD40L) rather than native fiber...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Thacker, Erin E., Nakayama, Masaharu, Smith, Bruce F., Bird, R. Curtis, Muminova, Zhanat, Strong, Theresa, Timares, Laura, Korokhov, Nikolay, O'Neill, Ann Marie, de Gruijl, Tanja D., Glasgow, Joel N., Tani, Kenzaburo, Curiel, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784276/
https://ncbi.nlm.nih.gov/pubmed/19786146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.09.055
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados