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Strategies to overcome host immunity to adenovirus vectors in vaccine development
The first clinical evaluations of adenovirus (Ad)-based vectors for gene therapy were initiated in the mid-1990s and led to great anticipation for future utility. However, excitement surrounding gene therapy, particularly Ad-based therapy, was diminished upon the death of Jesse Gelsinger, and recent...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3700409/ https://ncbi.nlm.nih.gov/pubmed/19485756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/erv.09.29 |
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