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An Electrochemical Sensor for Single Nucleotide Polymorphism Detection in Serum Based on a Triple-Stem DNA Probe

We report here an electrochemical approach that offers, for the first time, single-step, room-temperature single nucleotide polymorphism (SNP) detection directly in complex samples (such as blood serum) without the need for target modification, post-washing or the addition of exogenous reagents. Thi...

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Detalhes bibliográficos
Main Authors: Xiao, Yi, Lou, Xinhui, Uzawa, Takanori, Plakos, Kory J.I., Plaxco, Kevin W., Soh, H. Tom
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783950/
https://ncbi.nlm.nih.gov/pubmed/19807078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja905068s
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