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In vitro selection of structure-switching, self-reporting aptamers
We describe an innovative selection approach to generate self-reporting aptamers (SRAs) capable of converting target-binding events into fluorescence readout without requiring additional modification, optimization, or the use of DNA helper strands. These aptamers contain a DNAzyme moiety that is ini...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922547/ https://ncbi.nlm.nih.gov/pubmed/20660786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009172107 |
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