Wird geladen...

In vitro selection of structure-switching, self-reporting aptamers

We describe an innovative selection approach to generate self-reporting aptamers (SRAs) capable of converting target-binding events into fluorescence readout without requiring additional modification, optimization, or the use of DNA helper strands. These aptamers contain a DNAzyme moiety that is ini...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Oh, Seung Soo, Plakos, Kory, Lou, Xinhui, Xiao, Yi, Soh, H. Tom
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922547/
https://ncbi.nlm.nih.gov/pubmed/20660786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009172107
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!