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Fluorescence Detection of Single Nucleotide Polymorphisms via a Single, Self-Complementary, Triple-stem DNA Probe
We describe a single-step, single-component, fluorescence-based method of detecting single nucleotide polymorphisms at room temperature without exogenous reagents. The sensor is comprised of a single, self-complementary DNA strand forming a triple-stem structure, which undergoes a large conformation...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3053031/ https://ncbi.nlm.nih.gov/pubmed/19431180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.200900369 |
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