Fluorescence Detection of Single Nucleotide Polymorphisms via a Single, Self-Complementary, Triple-stem DNA Probe

We describe a single-step, single-component, fluorescence-based method of detecting single nucleotide polymorphisms at room temperature without exogenous reagents. The sensor is comprised of a single, self-complementary DNA strand forming a triple-stem structure, which undergoes a large conformation...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Xiao, Yi, Plakos, Kory J.I., Lou, Xinhui, White, Ryan J., Qian, Jiangrong, Plaxco, Kevin W., Soh, H. Tom
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053031/
https://ncbi.nlm.nih.gov/pubmed/19431180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.200900369
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki