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Novel graft copolymers enhance in vitro delivery of antisense oligonucleotides in the presence of serum
Antisense technology holds tremendous potential in the research and clinical settings. However, successful delivery of antisense oligodeoxynucleotides (ODNs) to the intracellular site of action requires the passage of many barriers, including survival against extracellular serum nucleases and escape...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2783907/ https://ncbi.nlm.nih.gov/pubmed/19699243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2009.08.008 |
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