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Novel graft copolymers enhance in vitro delivery of antisense oligonucleotides in the presence of serum

Antisense technology holds tremendous potential in the research and clinical settings. However, successful delivery of antisense oligodeoxynucleotides (ODNs) to the intracellular site of action requires the passage of many barriers, including survival against extracellular serum nucleases and escape...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Peddada, Lavanya Y., Harris, Nicole K., Devore, David I., Roth, Charles M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783907/
https://ncbi.nlm.nih.gov/pubmed/19699243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2009.08.008
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