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Dual targeting improves microbubble contrast agent adhesion to VCAM-1 and P-selectin under flow
To improve ultrasound contrast agents targeted to the adhesion molecules P-selectin and VCAM-1 for the purpose of molecular imaging of atherosclerotic plaques, perfluorocarbon-filled phospholipid microbubble contrast agents were coupled by a polyethylene glycol-biotin-streptavidin bridge with mAb MV...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2783796/ https://ncbi.nlm.nih.gov/pubmed/19666063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2009.08.001 |
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