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scVEGF Microbubble Ultrasound Contrast Agents: A Novel Probe for Ultrasound Molecular Imaging of Tumor Angiogenesis

OBJECTIVE: To develop a novel microbubble (MB) ultrasound contrast agent covalently coupled to a recombinant single-chain vascular endothelial growth factor construct (scVEGF) through uniform site-specific conjugation for ultrasound imaging of tumor angiogenesis. METHODS: Ligand conjugation to malei...

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Bibliografski detalji
Glavni autori: Christopher R., Anderson, Joshua J., Rychak, Marina, Backer, Joseph, Backer, Klaus, Ley, Alexander L., Klibanov
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426362/
https://ncbi.nlm.nih.gov/pubmed/20733505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/RLI.0b013e3181efd581
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