Singularity in polarization: re-wiring yeast cells to make two buds

For migrating cells, budding yeast, and many other cells, it is critical that polarization occur towards one, and only one, site (the singularity rule). Polarity establishment involves amplification of Cdc42 foci via positive feedback, but the basis for singularity was unclear. To assess whether or...

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Main Authors: Howell, Audrey S., Savage, Natasha S., Johnson, Sam A., Bose, Indrani, Wagner, Allison W., Zyla, Trevin R., Nijhout, H. Frederik, Reed, Michael C., Goryachev, Andrew B., Lew, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783644/
https://ncbi.nlm.nih.gov/pubmed/19914166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.10.024
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