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Singularity in polarization: re-wiring yeast cells to make two buds

For migrating cells, budding yeast, and many other cells, it is critical that polarization occur towards one, and only one, site (the singularity rule). Polarity establishment involves amplification of Cdc42 foci via positive feedback, but the basis for singularity was unclear. To assess whether or...

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Autores principales: Howell, Audrey S., Savage, Natasha S., Johnson, Sam A., Bose, Indrani, Wagner, Allison W., Zyla, Trevin R., Nijhout, H. Frederik, Reed, Michael C., Goryachev, Andrew B., Lew, Daniel J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783644/
https://ncbi.nlm.nih.gov/pubmed/19914166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.10.024
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