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Optimized subunit vaccine protects against experimental leishmaniasis

Development of a protective subunit vaccine against Leishmania spp. depends on antigens and adjuvants that induce appropriate immune responses. We evaluated a second generation polyprotein antigen (Leish-110f) in different adjuvant formulations for immunogenicity and protective efficacy against Leis...

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Detalhes bibliográficos
Main Authors: Bertholet, Sylvie, Goto, Yasuyuki, Carter, Lauren, Bhatia, Ajay, Howard, Randall F., Carter, Darrick, Coler, Rhea N., Vedvick, Thomas S., Reed, Steven G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783536/
https://ncbi.nlm.nih.gov/pubmed/19786136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.09.066
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