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Protective immunization against visceral leishmaniasis using Leishmania sterol 24-c-methyltransferase formulated in adjuvant

We present here the identification and characterization of Leishmania sterol 24-c-methyltransferase (SMT), as well as data on protection of mice immunized with this Ag formulated in MPL(®)-SE. Serological evaluation revealed that SMT is recognized by VL patients. C57BL/6 mice immunized with this vac...

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Bibliografische gegevens
Hoofdauteurs: Goto, Yasuyuki, Bogatzki, Lisa Y., Bertholet, Sylvie, Coler, Rhea N., Reed, Steven G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077354/
https://ncbi.nlm.nih.gov/pubmed/17804125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.08.001
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