Transport of Purines and Purine Salvage Pathway Inhibitors by the Plasmodium falciparum Equilibrative Nucleoside Transporter PfENT1

Plasmodium falciparum is a purine auxotroph. The transport of purine nucleosides and nucleobases from the host erythrocyte to the parasite cytoplasm is essential to support parasite growth. P. falciparum Equilibrative Nucleoside Transporter 1 (PfENT1) is a major route for purine transport across the...

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Bibliographic Details
Main Authors: Riegelhaupt, Paul M., Cassera, María B., Fröhlich, Richard F. G., Hazleton, Keith Z., Hefter, Jonathan J., Schramm, Vern L., Akabas, Myles H.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783484/
https://ncbi.nlm.nih.gov/pubmed/19818813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2009.10.001
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