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Mechanistic and structural insights into the proteolytic activation of Vibrio cholera MARTX toxin

MARTX toxins modulate the virulence of a number of Gram-negative Vibrio species. This family of toxins is defined by the presence of a cysteine protease domain (CPD), which proteolytically activates the Vibrio cholerae MARTX toxin. Although recent structural studies of the CPD have uncovered a novel...

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Detalhes bibliográficos
Main Authors: Shen, Aimee, Lupardus, Patrick J., Albrow, Victoria E., Guzzetta, Andrew, Powers, James C., Garcia, K. Christopher, Bogyo, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783333/
https://ncbi.nlm.nih.gov/pubmed/19465933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.178
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