ANDROGENIC SUPPRESSION OF SPREADING DEPRESSION IN FAMILIAL HEMIPLEGIC MIGRAINE TYPE 1 MUTANT MICE

Familial hemiplegic migraine type 1 (FHM1), a severe migraine with aura variant, is caused by mutations in the CACNA1A gene. Mutant mice carrying the FHM1 R192Q mutation exhibit increased propensity for cortical spreading depression (CSD), a propagating wave of neuroglial depolarization implicated i...

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Bibliographic Details
Main Authors: Eikermann-Haerter, Katharina, Baum, Michael J., Ferrari, Michel D., Maagdenberg, Arn M. J. M. van den, Moskowitz, Michael A., Ayata, Cenk
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783310/
https://ncbi.nlm.nih.gov/pubmed/19847904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21779
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