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A structural view on the mechanism of the ribosome-catalyzed peptide bond formation

The ribosome is a large ribonucleoprotein particle that translates zgenetic information encoded in mRNA into specific proteins. Its highly conserved active site, the peptidyl-transferase center (PTC), is located on the large (50S) ribosomal subunit and is comprised solely of rRNA, which makes the ri...

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Detalles Bibliográficos
Main Authors: Simonović, Miljan, Steitz, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783306/
https://ncbi.nlm.nih.gov/pubmed/19595805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2009.06.006
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