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Cross-crystal averaging reveals that the structure of the peptidyl-transferase center is the same in the 70S ribosome and the 50S subunit

Recently, two crystal structures of the Thermus thermophilus 70S ribosome in the same functional state were determined at 2.8 and 3.7 Å resolution but were different throughout. The most functionally significant structural differences are in the conformation of the peptidyl-transferase center (PTC)...

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Detalhes bibliográficos
Main Authors: Simonović, Miljan, Steitz, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206565/
https://ncbi.nlm.nih.gov/pubmed/18187576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711076105
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