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Peptidyl-CCA deacylation on the ribosome promoted by induced fit and the O3′-hydroxyl group of A76 of the unacylated A-site tRNA
The last step in ribosome-catalyzed protein synthesis is the hydrolytic release of the newly formed polypeptide from the P-site bound tRNA. Hydrolysis of the ester link of the peptidyl-tRNA is stimulated normally by the binding of release factors (RFs). However, an unacylated tRNA or just CCA bindin...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2578858/ https://ncbi.nlm.nih.gov/pubmed/18818369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1118908 |
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