Impact of Changing From Cyclosporine to Tacrolimus on Pharmacokinetics of Mycophenolic acid in Renal Transplant Recipients With Diabetes

The rate of mycophenolic acid (MPA) absorption after oral administration of mycophenolate mofetil (MMF) is delayed in patients with diabetes. Cyclosporine (CsA) decreases MPA exposure by inhibiting enterohepatic recirculation of MPA/MPA glucuronide, and tacrolimus (TRL) may alter the rate and extent...

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Hlavní autoři: Park, Jeong M., Lake, Kathleen D., Cibrik, Diane M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783237/
https://ncbi.nlm.nih.gov/pubmed/18708992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FTD.0b013e3181858169
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