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Selective control of gene expression by CDK9 in human cells

CDK9 associates with T-type cyclins and positively regulates transcriptional elongation by phosphorylating RNA polymerase II (RNAPII) and Negative Elongation Factors. However, it is unclear whether CDK9 is required for transcription of most genes by RNAPII or alternatively plays a role regulating th...

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Bibliografiske detaljer
Main Authors: Garriga, Judit, Xie, Hongbo, Obradovic, Zoran, Graña, Xavier
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783197/
https://ncbi.nlm.nih.gov/pubmed/19780058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21938
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