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Complex effects of flavopiridol on the expression of primary response genes

BACKGROUND: The Positive Transcription Elongation Factor b (P-TEFb) is a complex of Cyclin Dependent Kinase 9 (CDK9) with either cyclins T1, T2 or K. The complex phosphorylates the C-Terminal Domain of RNA polymerase II (RNAPII) and negative elongation factors, stimulating productive elongation by R...

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Detalles Bibliográficos
Main Authors: Keskin, Havva, Garriga, Judit, Georlette, Daphne, Graña, Xavier
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3339560/
https://ncbi.nlm.nih.gov/pubmed/22458775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-7-11
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