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Notch1 Represses Osteogenic Pathways in Aortic Valve Cells

Calcific aortic stenosis is the third leading cause of adult heart disease and the most common form of acquired valvular disease in developed countries. However, the molecular pathways leading to calcification are poorly understood. We reported two families in which heterozygous mutations in NOTCH1...

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Détails bibliographiques
Auteurs principaux: Nigam, Vishal, Srivastava, Deepak
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783189/
https://ncbi.nlm.nih.gov/pubmed/19695258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.08.008
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