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Notch1 Represses Osteogenic Pathways in Aortic Valve Cells

Calcific aortic stenosis is the third leading cause of adult heart disease and the most common form of acquired valvular disease in developed countries. However, the molecular pathways leading to calcification are poorly understood. We reported two families in which heterozygous mutations in NOTCH1...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nigam, Vishal, Srivastava, Deepak
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783189/
https://ncbi.nlm.nih.gov/pubmed/19695258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.08.008
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