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CD8 Lineage Commitment in the Absence of CD8

The absence of cytotoxic T lymphocyte activity and the failure of MHC class I–restricted T cell receptor (TCR) transgenic thymocytes to mature in CD8α-deficient mice suggest that CD8 may be essential for CD8 lineage commitment. We report that variants of the antigenic peptide that delete TCR transge...

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Main Authors: Goldrath, Ananda W., Hogquist, Kristin A., Bevan, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782926/
https://ncbi.nlm.nih.gov/pubmed/9175841
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