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Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs
Transfection of small RNAs (si/miRNAs) into cells typically lowers expression of many genes. Unexpectedly, increased expression of genes also occurs. We investigated whether this upregulation results from a saturation effect, i.e. competition for intracellular small RNA processing machinery between...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2009
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2782465/ https://ncbi.nlm.nih.gov/pubmed/19465925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1543 |
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