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Evaluation of Potential Therapies for a Mouse Model of Human Age-Related Macular Degeneration Caused by Delayed all-trans-Retinal Clearance
PURPOSE: Evaluate the efficacy of potential therapeutics in Rdh8(−/−) Abca4(−/−)mice, a rodent model of human age-related macular degeneration (AMD). METHODS: Therapeutic efficacy of several antioxidant agents (ascorbic acid, α-lipoic acid, α-tocopherol, Mn(III)-tetrakis(4-benzoic acid)-porphyrin, a...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2782428/ https://ncbi.nlm.nih.gov/pubmed/19494204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-3581 |
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