Effects of inactivation-resistant agonists on the signalling, desensitization and down-regulation of bradykinin B(2) receptors

BACKGROUND AND PURPOSE: A peptide bradykinin (BK) B(2) receptor agonist partially resistant to degradation, B-9972, down-regulates this receptor subtype. We have used another recently described non-peptide agonist, compound 47a, as a tool to study further the effects of metabolically more stable and...

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Detalhes bibliográficos
Main Authors: Bawolak, Marie-Thérèse, Fortin, Sébastien, Bouthillier, Johanne, Adam, Albert, Gera, Lajos, C-Gaudreault, René, Marceau, François
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782347/
https://ncbi.nlm.nih.gov/pubmed/19785654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00409.x
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