Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands

The semi-invariant natural killer (NK) T-cell receptor (NKTcr) recognises structurally diverse glycolipid antigens presented by the monomorphic CD1d molecule. While the α-chain of the NKTcr is invariant, the β-chain is more diverse, but how this diversity enables the NKTcr to recognise diverse antig...

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Autores principales: Florence, William C, Xia, Chengfeng, Gordy, Laura E, Chen, Wenlan, Zhang, Yalong, Scott-Browne, James, Kinjo, Yuki, Yu, Karl O A, Keshipeddy, Santosh, Pellicci, Daniel G, Patel, Onisha, Kjer-Nielsen, Lars, McCluskey, James, Godfrey, Dale I, Rossjohn, Jamie, Richardson, Stewart K, Porcelli, Steven A, Howell, Amy R, Hayakawa, Kyoko, Gapin, Laurent, Zajonc, Dirk M, Wang, Peng George, Joyce, Sebastian
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782097/
https://ncbi.nlm.nih.gov/pubmed/19816402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.286
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