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Phosphorylated Intrinsically Disordered Region of FACT Masks Its Nucleosomal DNA Binding Elements
FACT is a heterodimer of SPT16 and SSRP1, which each contain several conserved regions in the primary structure. The interaction of FACT with nucleosomes induces chromatin remodeling through the combinatorial action of its distinct functional protein regions. However, there is little mechanistic ins...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2782050/ https://ncbi.nlm.nih.gov/pubmed/19605348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.001958 |
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